Djibouti's location in a conflict-prone region—with Yemen, Eritrea, Somalia and Ethiopia at its borders—combined with its commitment to peaceful, moderate views makes it a unique and strategic partner for the United States. Djibouti is home to one of the few warehouses, not based in the United States, that prepositions American food aid for Africa and Asia, thus reducing the delivery times to areas in need by 75 percent.

Although a small country, it is making progress toward social and economic development. The government has spearheaded the creation of the only deep-sea port in the region, increasing private sector investment and contributing to gains in health and education. Despite these successes, the country continues to face significant challenges. USAID's work  invests in people through education, health, governance and democracy programs.